If you are experiencing any sort of discomfort or have sores in the boxer-short area you may want to get tested for HSV 2. The difference between HSV 1 and 2 is that Herpes 1 is typically associated with cold sores around the mouth or lip and 2 is typically associated with the genital area. HSV 1 & 2 can be tested using a IgG blood test or with a swob.